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The influence of environmental factors on key physical parameters of soccer players during competitive match-play have been widely investigated in the literature, although little is known on the effects of sub-zero ambient temperatures on the performance of adult elite soccer players during competitive matches. The aim of this study was to assess how the teams' match running performance indicators are related to low ambient temperature during competitive matches in the Russian Premier League. A total of 1142 matches played during the 2016/2017 to 2020/2021 seasons were examined. Linear mixed models were used to assess the relationships between changes in ambient temperature at the start of the match and changes in selected team physical performance variables, including total, running (4.0 to 5.5 m/s), high-speed running (5.5 to 7.0 m/s) and sprint (> 7.0 m/s) distances covered. The total, running and high-speed running distances showed no significant differences across temperatures up to 10°C, while these showed small to large decreases at 11 to 20°C and especially in the >20°C ranges. On the contrary, sprint distance was significantly lower at temperature of -5°C or less compared to higher temperature ranges. At sub-zero temperatures, every 1°C lower reduced team sprint distance by 19.2 m (about 1.6%). The present findings show that a low ambient temperature is negatively related to physical match performance behavior of elite soccer players, notably associated with a reduced total sprint distance.

Deuterated water (2H2O) is widely used for measuring de novo lipogenesis (DNL). 2H is incorporated into fatty acids via exchange between body water and the hydrogens of acetyl-CoA, malonyl-CoA, and NADPH. Previous studies concluded that these exchanges are incomplete; therefore, fatty acid 2H enrichment requires correcting. In mice, we measured the 2H enrichment of fatty acid positions 2 and 3 and methyl hydrogens from [U-2H7]glucose to determine 2H transfer from glucose to fatty acid via malonyl-CoA, NADPH, and acetyl-CoA, respectively. Positional fatty acid 2H enrichments were compared with 13C enrichment of the same sites from an equivalent amount of [U-13C6]glucose provided alongside the [U-2H7]glucose tracer. Transfer of glucose 2H to fatty acid position 2 and methyl sites was low (2H enrichment of 0.06 ± 0.01 and 0.14 ± 0.01 relative to 13C) indicating extensive exchange at both malonyl- and acetyl-CoA, respectively. Transfer of glucose 2H into fatty acid position 3 was more extensive (0.46 ± 0.04 relative to 13C, P < 10−5 vs. position 2), indicating a more limited exchange of those glucose hydrogens that were transferred via NADPH. However, mice provided with [U-13C6]glucose and 2H2O had equivalent 2H enrichments of fatty acid positions 2 and 3, suggesting that in this setting, NADPH and body water 2H had exchanged extensively. This is explained by contributions of substrates other than exogenous glucose to DNL coupled with their extensive 2H enrichment from 2H2O prior to DNL. Under such conditions, 2H enrichment of fatty acids from 2H2O does not need correction.

Ovulatory disorders are common causes of amenorrhea, abnormal uterine bleeding and infertility and are frequent manifestations of polycystic ovary syndrome (PCOS). There are many potential causes and contributors to ovulatory dysfunction that challenge clinicians, trainees, educators, and those who perform basic, translational, clinical and epidemiological research. Similarly, therapeutic approaches to ovulatory dysfunction potentially involve a spectrum of lifestyle, psychological, medical and procedural interventions. Collaborative research, effective education and consistent clinical care remain challenged by the absence of a consensus comprehensive system for classification of these disorders. The existing and complex system, attributed to the World Health Organization (WHO), was developed more than three decades ago and did not consider more than 30 years of research into these disorders in addition to technical advances in imaging and endocrinology. This article describes the development of a new classification of ovulatory disorders performed under the aegis of the International Federation of Gynecology and Obstetrics (FIGO) and conducted using a rigorously applied Delphi process. The stakeholder organizations and individuals who participated in this process comprised specialty journals, experts at large, national, specialty obstetrical and gynecological societies, and informed lay representatives. After two face-to-face meetings and five Delphi rounds, the result is a three-level multi-tiered system. The system is applied after a preliminary assessment identifies the presence of an ovulatory disorder. The primary level of the system is based on an anatomic model (Hypothalamus, Pituitary, Ovary) that is completed with a separate category for PCOS. This core component of the system is easily remembered using the acronym HyPO-P. Each anatomic category is stratified in the second layer of the system to provide granularity for investigators, clinicians and trainees using the 'GAIN-FIT-PIE' mnemonic (Genetic, Autoimmune, Iatrogenic, Neoplasm; Functional, Infectious and Inflammatory, Trauma and Vascular; Physiological, Idiopathic, Endocrine). The tertiary level allows for specific diagnostic entities. It is anticipated that, if widely adopted, this system will facilitate education, clinical care and the design and interpretation of research in a fashion that better informs progress in this field. Integral to the deployment of this system is a periodic process of reevaluation and appropriate revision, reflecting an improved understanding of this collection of disorders.

Resumen: Sobre la base de un marco conceptual post-foucaultiana nos fijamos en las racionalidades que informan a la organización de las comidas de los escolares portugueses y la aplicación de estas racionalidades para transformar y normalizan los hábitos alimenticios de los niños. El material empírico se extrae de un análisis documental del marco temático regulador de las comidas escolares desde la década de 1970 hasta la actualidad. Los objetivos son tres: 1) describir las continuidades y discontinuidades de los discursos oficiales sobre las comidas escolares; 2) ver de qué forma los niños, su salud y los alimentos aparecen y son interpretados en esos documentos; 3) describir y explicar las trayectorias de las gubernamentalidades y su pluralidad de acuerdos relativos a las comidas escolares. Fue posible identificar cinco tipos de regímenes gubernamentales de comidas escolares: la autoritaria; la demócrata, la moderna, el consumidor y la de Obesidad y Riesgo. Estos regímenes se entrelazan y organizan en múltiples formas los contextos que rigen las prácticas de alimentación de los niños en las escuelas. Abstract: Drawing on a post-Foucauldian conceptual framework we look at the rationalities that inform the organization of the Portuguese school meals and the implementation of these rationalities to transform and normalize children eating habits. The empirical material is drawn from a thematic documental analysis of the school meals regulatory framework from the 1970s up until nowadays. The objectives are threefold: 1) to describe the continuities and discontinuities of official discourses on school meals institutional practices; 2) to look at the ways children, health and food are placed and interpreted in those documents; 3) to describe and explain trajectories of school meals governmentalities and its plural arrangements. It was possible to identify five types of school meals governmental regimes: the Authoritarian; the Democratic, the Modern, the Consumer and the Obesity and Risk. These regimes are intertwined and organize in multiple ways the contexts that govern childrens eating practices in schools.

The article reports a clinical case of a 39-year-old male patient who was admitted in the emergency room in shock. The clinical exams and additional tests identified a right massive hemothorax, without apparent etiological factors. He was submitted to an emergency right thoracotomy. A bulky varicose formation in the diaphragmatic surface, with evident laceration and haemorrhage was identified. The article describes this case due to its rarity. The varicose formation was simply ligated and the evolution, as well as the outcome of this clinical case was uneventful.

Evaluation of semen characteristics after hormonal induction of the bullfrog could provide valuable information on the gametes of this species, which may be useful for projects related to artificial fertilization, animal improvement, and cryopreservation. Bullfrog males were induced to spermiate with buserelin acetate (GnRHa), and their semen was subsequently analyzed. GnRHa (0.4 μg) was administered to the bullfrog males with secondary sexual characteristics such as weight > 200 g, yellow chin, nuptial callus, and amplexus reflex, being the semen collected after 60 min. The semen volume was 5.76 mL, light-colored. The other characteristics of the semen were: vigor of 4.80, motility of 93%, concentration of 14.24 × 106 mL-1, and content of normal spermatozoa of 70%. The volume, color, vigor, motility, sperm concentration, and content of normal spermatozoa were adequate in these bullfrog semen samples. Evaluation of the bullfrog semen samples based on this set of parameters is essential for decision-making about the quality and destination of the semen.